Core unit - fluorescence-activated cell sorting
Electronic cell sorting based on multi parameter flow cytometry have become essential methods in biomedical research. This unit offers full service in the field of FACS, it provides support in designing proper cell preparation and staining protocols suitable for the further experiments. The helpdesk platform for analytical and preparative methods is managed by an expertised operator with longtime experience in flow-cytometry and cell preparation.
This unit is open for all scientists necessitating very pure populations even out of rare events and valid FACS data. It is equiped with state of the art analyzers and cell-sorters.
Patra AK, Avots A, Zahedi RP, Schüler T, Sickmann A, Bommhardt U, Serfling E.
An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development. Nat Immunol. 2013 Feb;14(2):127-35.
Bommert KS, Effenberger M, Leich E, Küspert M, Murphy D, Langer C, Moll R, Janz S, Mottok A, Weissbach S, Rosenwald A, Bargou R, Bommert K
The feed-forward loop between YB-1 and MYC is essential for multiple myeloma cell survival.Leukemia. 2013 Feb;27(2):441-50.
Muhammad K1, Roll P, Seibold T, Kleinert S, Einsele H, Dörner T, Tony HP
Impact of IL-6 receptor inhibition on human memory B cells in vivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells.
Ann Rheum Dis. 2011 Aug;70(8):1507-10. doi: 10.1136/ard.2010.141325. Epub 2011 May 8.