Intern
    Onkologische Forschung

    Peter Gallant: Cellular and organismal growth

    Summary

    Our group investigates the pathways that control animal growth, both under physiological and under pathological conditions. We are particularly interested in the transcription factor and proto-oncogene Myc, its transcriptional targets and the molecular mechanism by which they are controlled. We use Drosophila melanogaster as a model system for these studies, and also to investigate additional signals that coordinate animal growth during development.

    Recent Publications

    Herter, E.K., Stauch, M., Gallant, M., Wolf, E., Raabe, T., and Gallant, P. (2015). snoRNAs are a novel class of biologically relevant Myc targets. BMC Biology 13, 25.

    Hovhanyan, A., Herter, E.K., Pfannstiel, J., Gallant, P., and Raabe, T. (2014). Drosophila mbm is a nucleolar myc and casein kinase 2 target required for ribosome biogenesis and cell growth of central brain neuroblasts. Mol. Cell. Biol. 34, 1878-1891.

    Gallant, P. (2013). Myc Function in Drosophila. Cold Spring Harb Perspect Med 3 (10), a014324; doi: 10.1101/cshperspect.a014324.

    Furrer, M., Balbi, M., Albarca-Aguilera, M., Gallant, M., Herr, W. and Gallant., P. (2010) Drosophila Myc interacts with Host Cell Factor (dHCF) to activate transcription and control growth. J. Biol. Chem. 285, 39623-39636.

    Steiger, D., Furrer, M., Schwinkendorf, D. and Gallant, P. (2008). Max-independent functions of Myc in Drosophila melanogaster. Nature Genetics 40, 1084-1091.

    Kontakt

    Comprehensive Cancer Center
    Haus C16
    Josef-Schneider Str. 6
    97080 Würzburg

    Tel.: +49 931 201-35350
    Fax: +49 931 201-35359
    E-Mail

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