Translational Next Generation Sequencing
This program focuses on the identification of tumor-specific mutations by sequencing of genomes of individual tumors. High throughput sequencing projects are ongoing in non-Hodgkin lymphoma, multiple myeloma, Wilms tumor and melanoma as part of national and international consortia on cancer genomics (e.g. ICGC, TCGA). Sequencing of multiple myeloma and non-Hodgkin lymphoma exomes was performed at the CCC and led to the identification of novel target structures. Parts of this work have laid the foundations for the development of new targeted and personalized therapies for these cancers.
Program Coordinator: Andreas Rosenwald